Secreted Virus–Encoded Proteins Reflect Murine Cytomegalovirus Productivity in Organs

Identification of proteins associated with murine cytomegalovirus virions.

Proteins associated with the murine cytomegalovirus (MCMV) viral particle were identified by a combined approach of proteomic and genomic methods. Purified MCMV virions were dissociated by complete denaturation and subjected to either separation by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and in-gel digestion or treated directly by in-solution tryptic digestion. Peptides were s...

Characterization of Murine Cytomegalovirus

The Murine Cytomegalovirus

Secreted Immunomodulatory Viral Proteins

effects of macrophages in resistance to murine cytomegalovirus infection

in a preliminary experiment. the protective effects of ' peritoneal macrophages was shown by transferring macroph. ages fr-om adult mice to newborn and to 7 and 14 days old mice. it suckling mice from intraperitoneal infection with mcmv by reducing the mortality rate from 100% to 27%.was demontrated that such transplentatton protect